{"id":41,"date":"2023-11-22T20:46:26","date_gmt":"2023-11-22T20:46:26","guid":{"rendered":"https:\/\/drtaniadempsey.com\/?page_id=41"},"modified":"2023-11-27T22:23:49","modified_gmt":"2023-11-27T22:23:49","slug":"supportive-oligonucleotide-technique","status":"publish","type":"page","link":"https:\/\/drtaniadempsey.com\/supportive-oligonucleotide-technique\/","title":{"rendered":"Supportive Oligonucleotide Technique"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;4&#8243; bottom_padding=&#8221;4&#8243; back_color=&#8221;color-153429&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;793447&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_percent=&#8221;100&#8243; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;256339&#8243;][vc_custom_heading heading_semantic=&#8221;h1&#8243; text_size=&#8221;h1&#8243; text_transform=&#8221;uppercase&#8221; css_animation=&#8221;single-curtain&#8221; uncode_shortcode_id=&#8221;236010&#8243;]SOT (Supportive Oligonucleotide Technique)[\/vc_custom_heading][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;5&#8243; bottom_padding=&#8221;5&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;810009&#8243;][vc_column width=&#8221;1\/1&#8243;][vc_row_inner row_inner_height_percent=&#8221;0&#8243; overlay_alpha=&#8221;50&#8243; equal_height=&#8221;yes&#8221; gutter_size=&#8221;4&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;186656&#8243; limit_content=&#8221;&#8221;][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image media=&#8221;556&#8243; media_width_percent=&#8221;100&#8243; uncode_shortcode_id=&#8221;203137&#8243; el_class=&#8221;box-shadow-left&#8221;][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;168799&#8243;][vc_custom_heading text_transform=&#8221;uppercase&#8221; uncode_shortcode_id=&#8221;444379&#8243;]What is SOT Therapy?[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;627848&#8243;]SOT is a type of therapy based on antisense oligonucleotide technique (ASOT) that is a technology that is being utilized and studied in various diseases, including cancer.<\/p>\n<p>SOT is now being used as a treatment for Lyme bacteria, co-infections, and viruses like EBV, HSV, CMV, Varicella and others. This breakthrough therapy utilizes short DNA or RNA segments to block the expression of critical segments of genes needed for certain microbes to survive and replicate.<\/p>\n<p>SOT creates a shutoff \u201ckey\u201d that precisely fits a chosen \u201clock\u201d portion of a pathogen. The \u201clock\u201d is a specific section of DNA that normally controls an important function of the pathogen. The \u201ckey\u201d binds to the \u201clock\u201d and blocks the function thus eliminating the pathogen. Afterwards, the SOT compound is released and travels to the next target, thus fighting the infection 24\/7 for up to 6 months.<\/p>\n<p>SOT works by creating a short segment of mRNA in the lab that binds to the specific DNA segments and prevents the bacteria from making essential proteins, essentially shutting off bacterial replication. Unable to replicate, the bacteria is unable to cause disease.[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;5&#8243; bottom_padding=&#8221;5&#8243; back_color=&#8221;color-125020&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;527022&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column width=&#8221;1\/1&#8243;][vc_custom_heading text_transform=&#8221;uppercase&#8221; uncode_shortcode_id=&#8221;158640&#8243;]What is the process for getting SOT, from start to finish?[\/vc_custom_heading][uncode_list icon=&#8221;fa fa-arrow-right2&#8243; icon_color=&#8221;color-148261&#8243; uncode_shortcode_id=&#8221;122288&#8243; icon_color_type=&#8221;uncode-palette&#8221;]<\/p>\n<ul>\n<li>Specialized blood testing will be done in our office to confirm the presence of a specific infection or co-infection.<\/li>\n<li>Upon reviewing the results with you, your doctor will then decide which pathogen to order SOT for.<\/li>\n<li>Your blood is then drawn again in our office to be sent to the RGCC laboratory in Greece.<\/li>\n<li>After about 4 weeks, your oligonucleotide molecules (SOT) will arrive in our office and you will return to have your SOT administered intravenously. The SOT infusion takes approximately 2 hours.<\/li>\n<li>Six weeks after SOT, co-infections may flare and retesting with your doctor may need to be done. Six months post-SOT, additional lab testing will be done to see how you are progressing.<\/li>\n<\/ul>\n<p>[\/uncode_list][vc_column_text uncode_shortcode_id=&#8221;132407&#8243;]The main side effects of SOT treatment are detox or \u201cHerx\u201d reactions, such as fatigue, body aches, and headache. Some patients experience no side effects but others will have mild to moderate reactions and the onset of these reactions varies from patient to patient.<\/p>\n<p>The SOT for a particular infection may be repeated up to 3x per year if needed. With each round of SOT it is recommended to retest for the presence of other pathogens. At some point the infection may be completely eradicated or remain stable in a quiet remission.[\/vc_column_text][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;5&#8243; bottom_padding=&#8221;5&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;810009&#8243;][vc_column column_width_percent=&#8221;100&#8243; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;428825&#8243;][vc_custom_heading text_transform=&#8221;uppercase&#8221; separator=&#8221;yes&#8221; separator_color=&#8221;yes&#8221; uncode_shortcode_id=&#8221;212143&#8243;]What pathogens does SOT target?[\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][vc_custom_heading heading_semantic=&#8221;h4&#8243; text_size=&#8221;h4&#8243; text_weight=&#8221;600&#8243; text_transform=&#8221;uppercase&#8221; uncode_shortcode_id=&#8221;178215&#8243;]Lyme-related[\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][vc_row_inner row_inner_height_percent=&#8221;0&#8243; overlay_alpha=&#8221;50&#8243; equal_height=&#8221;yes&#8221; gutter_size=&#8221;3&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;398193&#8243; limit_content=&#8221;&#8221;][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; override_padding=&#8221;yes&#8221; column_padding=&#8221;3&#8243; back_color=&#8221;color-125020&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;207134&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column_text uncode_shortcode_id=&#8221;108643&#8243;]<strong>Borrelia<\/strong>[\/vc_column_text][uncode_list icon=&#8221;fa fa-check2&#8243; icon_color=&#8221;color-148261&#8243; uncode_shortcode_id=&#8221;766926&#8243; icon_color_type=&#8221;uncode-palette&#8221;]<\/p>\n<ul>\n<li>B.afzelii<\/li>\n<li>B.bissettii<\/li>\n<li>B.bavariensis<\/li>\n<li>B.burgdorferi<\/li>\n<li>B.californiesis<\/li>\n<li>B.finlandensis<\/li>\n<li>B.garinii<\/li>\n<li>B.genomospecies<\/li>\n<li>B.hermsii<\/li>\n<li>B.kurtenbachii<\/li>\n<li>B.lusitaniae<\/li>\n<li>B.mayonii<\/li>\n<li>B.miyamotoi<\/li>\n<li>B.recurrentis<\/li>\n<li>B.sinica<\/li>\n<li>B.turcica<\/li>\n<li>B.valaisiana<\/li>\n<li>Candidatus B.tachyglossi<\/li>\n<li>B.valaisiana<\/li>\n<\/ul>\n<p>[\/uncode_list][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; override_padding=&#8221;yes&#8221; column_padding=&#8221;3&#8243; back_color=&#8221;color-125020&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;523586&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column_text uncode_shortcode_id=&#8221;151834&#8243;]<strong>Bartonella<\/strong>[\/vc_column_text][uncode_list icon=&#8221;fa fa-check2&#8243; icon_color=&#8221;color-148261&#8243; uncode_shortcode_id=&#8221;676674&#8243; icon_color_type=&#8221;uncode-palette&#8221;]<\/p>\n<ul>\n<li>B.bacilliformis<\/li>\n<li>B.elizabethae<\/li>\n<li>B.henselae<\/li>\n<li>B.koehlerae<\/li>\n<li>B.quintana<\/li>\n<li>B.vinsonii<\/li>\n<\/ul>\n<p>[\/uncode_list][vc_column_text uncode_shortcode_id=&#8221;211566&#8243;]<strong>Babesia<\/strong>[\/vc_column_text][uncode_list icon=&#8221;fa fa-check2&#8243; icon_color=&#8221;color-148261&#8243; uncode_shortcode_id=&#8221;832740&#8243; icon_color_type=&#8221;uncode-palette&#8221;]<\/p>\n<ul>\n<li>B.bigemina<\/li>\n<li>B.bovis<\/li>\n<li>B.divergens<\/li>\n<li>B.duncani<\/li>\n<li>B.microti<\/li>\n<li>B.odocoilei<\/li>\n<\/ul>\n<p>[\/uncode_list][vc_column_text uncode_shortcode_id=&#8221;125356&#8243;]<strong>Other tick-borne bacteria<\/strong>[\/vc_column_text][uncode_list icon=&#8221;fa fa-check2&#8243; icon_color=&#8221;color-148261&#8243; uncode_shortcode_id=&#8221;193037&#8243; icon_color_type=&#8221;uncode-palette&#8221;]<\/p>\n<ul>\n<li>Anaplasma phagocytophilum<\/li>\n<li>Ehrlichia chaffeensis<\/li>\n<li>Rickettsia rickettsia<\/li>\n<\/ul>\n<p>[\/uncode_list][\/vc_column_inner][\/vc_row_inner][vc_empty_space empty_h=&#8221;2&#8243;][vc_separator sep_color=&#8221;&#8221; uncode_shortcode_id=&#8221;171239&#8243;][vc_empty_space empty_h=&#8221;2&#8243;][vc_custom_heading heading_semantic=&#8221;h4&#8243; text_size=&#8221;h4&#8243; text_weight=&#8221;600&#8243; text_transform=&#8221;uppercase&#8221; uncode_shortcode_id=&#8221;348853&#8243;]Virus-related[\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][vc_row_inner row_inner_height_percent=&#8221;0&#8243; overlay_alpha=&#8221;50&#8243; equal_height=&#8221;yes&#8221; gutter_size=&#8221;3&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;129903&#8243; limit_content=&#8221;&#8221;][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; override_padding=&#8221;yes&#8221; column_padding=&#8221;3&#8243; back_color=&#8221;color-125020&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;270839&#8243; back_color_type=&#8221;uncode-palette&#8221;][uncode_list icon=&#8221;fa fa-check2&#8243; icon_color=&#8221;color-148261&#8243; uncode_shortcode_id=&#8221;171632&#8243; icon_color_type=&#8221;uncode-palette&#8221;]<\/p>\n<ul>\n<li>HHV1\/HSV1 \u2014 (Human Simplex Virus-Oral-Facial)<\/li>\n<li>HHV2\/HSV2 \u2014 (Human Simplex Virus-Genital)<\/li>\n<li>HHV6 (A &amp; B) \u2014 (Human Herpes Virus 6)<\/li>\n<li>CMV \u2014 (Cytomegalovirus)<\/li>\n<li>Coxsackie (Type A &amp; B)<\/li>\n<li>VZV \u2014 Varicella-zoster (shingles)<\/li>\n<\/ul>\n<p>[\/uncode_list][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; override_padding=&#8221;yes&#8221; column_padding=&#8221;3&#8243; back_color=&#8221;color-125020&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;131830&#8243; back_color_type=&#8221;uncode-palette&#8221;][uncode_list icon=&#8221;fa fa-check2&#8243; icon_color=&#8221;color-148261&#8243; uncode_shortcode_id=&#8221;267378&#8243; icon_color_type=&#8221;uncode-palette&#8221;]<\/p>\n<ul>\n<li>EBV \u2014 (Epstein Barr)<\/li>\n<li>HPV (16\/18) \u2014 Human papillomavirus<\/li>\n<li>HPV (6\/11) \u2014 Human papillomavirus<\/li>\n<li>HBV \u2014 (hepatitis B)<\/li>\n<li>HCV \u2014 (hepatitis C)<\/li>\n<li>HIV \u2014 (human immunodeficiency virus)-AIDS<\/li>\n<li>HTLV1\u2014 (human T-cell lymphotropic virus)<\/li>\n<\/ul>\n<p>[\/uncode_list][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;5&#8243; bottom_padding=&#8221;5&#8243; back_color=&#8221;color-125020&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;527022&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column width=&#8221;1\/1&#8243;][vc_row_inner row_inner_height_percent=&#8221;0&#8243; overlay_alpha=&#8221;50&#8243; equal_height=&#8221;yes&#8221; gutter_size=&#8221;4&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;500850&#8243; limit_content=&#8221;&#8221;][vc_column_inner column_width_percent=&#8221;100&#8243; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;116384&#8243;][vc_custom_heading text_transform=&#8221;uppercase&#8221; uncode_shortcode_id=&#8221;180524&#8243;]How is SOT administered, and how long does it take?[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;830012&#8243;]The molecules are put into the body via an IV push that takes approximately 5 minutes. The entire process takes about 90-120 minutes because saline is also administered via an IV along with an antihistamine and steroids. You are watched in the clinic for approximately 2 hours to be sure there are no side-effects.[\/vc_column_text][\/vc_column_inner][vc_column_inner width=&#8221;1\/2&#8243;][vc_single_image media=&#8221;558&#8243; media_width_percent=&#8221;100&#8243; uncode_shortcode_id=&#8221;123405&#8243; el_class=&#8221;box-shadow-right&#8221;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;4&#8243; bottom_padding=&#8221;4&#8243; back_color=&#8221;color-493194&#8243; overlay_alpha=&#8221;70&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;200410&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_percent=&#8221;100&#8243; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;97&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;120257&#8243;][vc_custom_heading text_transform=&#8221;uppercase&#8221; uncode_shortcode_id=&#8221;169557&#8243;]Did you know?[\/vc_custom_heading][vc_column_text uncode_shortcode_id=&#8221;486207&#8243;]SOT is not a drug in the traditional sense. It is not an antibiotic nor is it gene therapy. It does not change the genetic structure. There is no gene splicing, gene insertion, or manipulation.<\/p>\n<p>SOT therapy is a stealth technology with molecules so small that they are able to avoid detection and destruction by the immune system or RNA degrading enzymes for months, allowing them to quietly circulate through the body, attaching to their viral or bacterial targets.[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;4&#8243; bottom_padding=&#8221;4&#8243; back_color=&#8221;color-153429&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;793447&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_percent=&#8221;100&#8243; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;3&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-41","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/drtaniadempsey.com\/wp-json\/wp\/v2\/pages\/41","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drtaniadempsey.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/drtaniadempsey.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/drtaniadempsey.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/drtaniadempsey.com\/wp-json\/wp\/v2\/comments?post=41"}],"version-history":[{"count":0,"href":"https:\/\/drtaniadempsey.com\/wp-json\/wp\/v2\/pages\/41\/revisions"}],"wp:attachment":[{"href":"https:\/\/drtaniadempsey.com\/wp-json\/wp\/v2\/media?parent=41"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}